The first time I was put on birth control I was 17 years old. I was getting a depo shot every three months. Being on depo caused me severe mood swings, depression, anxiety and I lost about 15 pounds. I felt irritable constantly and when I decided that I no longer wanted to be on birth control I had a very heavy period for about 2 weeks till it died off till I was spotting. Since then I have uncomfortable and thicker vaginal discharge.